How Saffron Affects Serotonin and Mood: The Mechanism
A Mechanism-First Deep Dive into Saffron's Neurobiological Effects and Clinical Impact
215 papers, tiered on a transparent rubric. Read the evidence your supplement rests on — before you swallow it.
A Mechanism-First Deep Dive into Saffron's Neurobiological Effects and Clinical Impact
How GABA Supplementation Alters Sleep Stages and Efficiency Through Receptor Mechanisms
Understanding the Size-Dependent Effects of Hyaluronic Acid on Human Inflammation and Skin Hydration
A Deep Dive into the Biomarker-Specific Effects and Personalizable Value of Krill Oil Supplementation
Why Your Liver Panel Predicts Spirulina's True Impact
Why your starting vitamin D level determines whether supplementation will help or do nothing
New RCTs reveal a lipid-lowering edge, but glucose effects depend on your metabolic profile
Personalizing Pomegranate Extract: Why Baseline Inflammation Levels Decide Whether You’ll Benefit
77 articles · Berberine · Vitamin B6 · Zinc
77 articles · Coq10 · Taurine · Berberine
89 articles · Ashwagandha · Omega 3 · Zinc
37 articles · Ashwagandha · Magnesium · L Citrulline
39 articles · Ashwagandha · Dhea · Vitamin D3
61 articles · Coq10 · Ashwagandha · Creatine
80 articles · Vitamin C · Astaxanthin · Vitamin D3
49 articles · Coq10 · Pqq · Taurine
26 articles · Berberine · Green Tea Extract · Inulin
6 articles · Collagen · Vitamin C · Biotin
We don’t rate supplements — we rate claims about supplements. A single ingredient can earn Strong evidence for one benefit and Insufficient for another. The tier tells you how seriously to take a specific conclusion, not the molecule in general.
At least two concordant RCTs with low-to-moderate risk of bias, or a high-certainty GRADE meta-analysis. This is where we feel confident saying yes.
One well-designed RCT plus replicated observational data. The signal is real; the effect size isn’t locked down.
Early human data, mixed results, or a single trial. We report it, but we don’t bet the farm on it.
Animal-only studies, mechanism-only claims, or anecdote. We index these so you know they exist, not so you swallow them.
12 featured · ~188 min
12 featured · ~174 min
12 featured · ~185 min
12 articles · ~186 min
12 articles · ~194 min
11 articles · ~189 min